3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7: Specifications, Uses, and Supplier Guide

Author: Justin

Aug. 18, 2026

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Tags: Chemicals

3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7: Specifications, Uses, and Supplier Guide

I use this guide to help pharmaceutical, agrochemical, and fine-chemical buyers evaluate 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid, identified by CAS 376592-93-7. The compound contains an amino group, a hydroxy group, a carboxylic acid group, and a biphenyl aromatic framework, so its suitability depends strongly on the intended synthetic route and required impurity profile. Because publicly available product information may differ between suppliers, buyers should confirm identity, analytical data, packaging, availability, and commercial terms directly before placing an order.

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Who This Guide Is For

This reference is intended for research and development teams, pharmaceutical intermediate buyers, process chemists, procurement specialists, and quality departments. It is especially useful when a project requires a multifunctional aromatic intermediate rather than a simple single-functional building block. I recommend using the information below as a supplier-evaluation framework, not as a substitute for a project-specific specification or analytical review.

Buyers at different development stages will have different priorities. An early discovery team may need a small quantity for route scouting, while a process-development group may require reproducible batch quality and a defined impurity package. Commercial sourcing teams normally focus on supply continuity, documentation, packaging, lead time, and the supplier’s ability to respond to technical questions.

Basic Chemical Context

3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 is an aromatic carboxylic acid with two additional reactive functionalities: an amino group and a phenolic hydroxy group. These groups can influence solubility, salt formation, hydrogen bonding, chromatographic behavior, and downstream reaction compatibility. The exact behavior of a supplied batch should be confirmed through analytical testing rather than inferred only from the chemical name.

The compound’s structure may make it relevant to multi-step synthesis in which selective functional-group transformation is required. The amino group can participate in reactions commonly used for aromatic amines, while the carboxylic acid can support coupling, esterification, or other derivatization strategies. The hydroxy group may also affect protection strategy and reaction selectivity, particularly when more than one functional group can react under the selected conditions.

Specifications Buyers Should Confirm

Identity and Composition

The first requirement is a clear identity package linked to CAS 376592-93-7 and the supplier’s internal product code. I would ask for the molecular formula, molecular weight, appearance, assay method, and the analytical techniques used to confirm identity. Commonly requested evidence may include an assay result, HPLC or LC-MS information, and supporting spectra such as NMR or infrared data, where available.

Do not assume that a stated purity percentage is directly comparable across suppliers. One supplier may report HPLC area percentage, while another may use a different calculation basis or report assay on a corrected basis. Before comparing quotations, ask each supplier to define the test method, reporting basis, reference standard status, and whether water, residual solvents, inorganic residues, or other related substances are included in the specification.

Physical and Handling Information

Appearance, particle form, and packaging can affect laboratory handling and process transfer. Buyers should confirm whether the material is supplied as a powder, whether it is hygroscopic, and whether special handling instructions are recommended. If the material is sensitive to moisture, light, heat, or prolonged storage, those conditions should be documented on the specification sheet or technical data provided by the supplier.

Storage and transport conditions should be agreed before shipment rather than assumed from the structure. The buyer should also request the recommended retest or review period and clarify how the supplier manages material that approaches that date. These details are particularly important when the material will be held for several months before use.

Potential Uses and Application Matching

This compound may be considered as a research or process intermediate for synthetic programs involving substituted biphenyl carboxylic acid structures. Its three functional groups provide several possible points for chemical transformation, but the practical route depends on reaction conditions, protection requirements, and the target molecule. I would not treat the chemical name alone as proof of suitability for a particular pharmaceutical or agrochemical application.

For medicinal chemistry, the material may be evaluated during analog synthesis where aromatic substitution and carboxylic acid functionality are important to the target design. For process chemistry, the main questions are usually reaction yield, impurity clearance, isolation behavior, and reproducibility at increased scale. For custom synthesis, the supplier may need to review the proposed route, expected quantity, analytical requirements, and restrictions on starting materials or processing conditions.

Maison Chemical supply professional and honest service.

Buyer requirement Information to confirm Why it matters
Identity CAS number, structure, formula, molecular weight, spectra Reduces the risk of ordering a similar aromatic intermediate
Purity Assay basis, related substances, water, residual solvents Supports route reproducibility and impurity control
Supply Available quantity, batch size, packaging, lead time Helps align procurement with laboratory or production planning
Documentation Specification, COA, SDS, shipping and export documents Supports internal quality and regulatory review

How to Select the Right Material Grade

Define the Intended Stage of Use

Start by identifying whether the material is for discovery research, route development, pilot work, or a later manufacturing stage. A discovery purchase may require only a small analytical sample, whereas process development normally requires batch-to-batch consistency and a fuller impurity profile. I suggest documenting the intended use before requesting quotations because it helps the supplier propose an appropriate grade and testing package.

For an initial feasibility study, an illustrative request may be 100 mg to 1 g, depending on the number of reactions and analytical experiments planned. A pilot or process-development request may instead be 1 kg to 5 kg, but the actual quantity should be calculated from the route, expected yield, sampling plan, and safety stock. These are planning examples, not product specifications or guaranteed package sizes.

Compare Analytical Requirements

Ask suppliers to quote against the same analytical requirements so that price comparisons remain meaningful. At minimum, I would compare the stated assay method, related-substance limits, water or solvent controls, appearance, and release documentation. If a critical impurity is known from the synthetic route, it should be listed explicitly rather than left to a general purity statement.

When scale increases, analytical comparability becomes more important. A material that performs well in a small experiment may still require additional review if the larger batch has a different particle profile, residual solvent pattern, or impurity distribution. Buyers should therefore consider requesting a representative batch sample or additional analytical data before approving a larger order.

Pricing, MOQ, and Lead-Time Considerations

The price of CAS 376592-93-7 can vary with quantity, purity target, synthesis route, testing requirements, packaging, and whether the material is stocked or produced against an order. A low unit price may not represent the lowest total procurement cost if it excludes special testing, additional packaging, export preparation, or extended lead time. Request a written quotation that separates product cost from any required technical or logistics charges.

Minimum order quantity is often connected to batch economics and raw-material availability. For planning purposes, buyers may compare a sample request of 100 mg, a development request of 1 kg, and a larger requirement above 5 kg, while recognizing that actual MOQ must be confirmed for each supplier and grade. Lead time can also change materially between stocked material and custom production; an indicative planning window of 2 to 8 weeks should be treated only as a discussion range, not as a delivery commitment.

Supplier Evaluation Checklist

Technical and Quality Questions

  • Can the supplier confirm the product identity against CAS 376592-93-7?
  • What assay method and reporting basis are used?
  • Which related substances are routinely monitored?
  • Can the supplier provide a current specification and batch-specific COA?
  • Are SDS, packing information, and transport classifications available for review?
  • Can the supplier discuss sample approval before a larger purchase?

Commercial and Service Questions

  • Is the material available from stock, or is it produced after order confirmation?
  • What are the sample quantity, MOQ, package options, and estimated lead time?
  • Can the supplier support repeat batches with consistent specifications?
  • How are changes to raw materials, process, site, or analytical methods communicated?
  • Can the supplier coordinate export documents and shipment requirements for the destination country?

A supplier should also communicate limitations clearly. If a requested purity, quantity, or delivery schedule requires technical review, the buyer should receive a qualified estimate rather than an unsupported promise. Transparent communication is especially valuable for multifunctional intermediates because the final specification may need to reflect the downstream reaction rather than a generic catalog standard.

How Maison Chemical Can Support Your Evaluation

At Maison Chemical, I approach this type of inquiry by first clarifying the target quantity, intended application, required purity, documentation, destination, and delivery schedule. Our role as a chemicals and pharmaceutical intermediates supplier is to help buyers translate a chemical requirement into a practical sourcing request. Product availability, batch information, testing scope, MOQ, and lead time should be confirmed for the specific order rather than assumed from a general listing.

We can discuss sample evaluation, specification alignment, packaging options, and the documentation needed for internal approval. If your project has a known impurity concern or a defined downstream reaction, sharing that information early can make the technical discussion more productive. We can then review whether the requested material and supply plan are suitable for your development stage.

Key Takeaways

  • 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 is a multifunctional aromatic carboxylic acid intermediate with amino, hydroxy, and carboxylic acid groups.
  • The chemical name alone does not establish assay, impurity profile, storage condition, or commercial availability.
  • Buyers should compare analytical methods, reporting basis, documentation, MOQ, packaging, and lead time on the same specification.
  • Illustrative planning quantities may range from 100 mg to 1 g for early evaluation and 1 kg to 5 kg for development, but actual supply terms require confirmation.

Conclusion and Next Steps

The best way to evaluate 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7 is to connect the chemical identity with your actual synthesis, analytical, and procurement requirements. I recommend preparing a short inquiry that states the target quantity, purity or assay expectation, key impurity concerns, packaging preference, destination, documentation requirements, and required delivery window. This gives suppliers enough information to respond with a relevant and reviewable offer.

For a quotation or technical discussion, contact Maison Chemical with your target specification and project stage. We can review the request for sample supply, development quantities, or larger-volume sourcing and confirm the applicable product details before order placement. The next practical step is to request a current specification, representative analytical information, commercial terms, and a delivery estimate for your required quantity.

Are you interested in learning more about 3'-Amino-2'-hydroxybiphenyl-3-carboxylic Acid CAS 376592-93-7? Contact us today to secure an expert consultation!

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