2-Bromophenylboronic Acid CAS 244205-40-1 Supplier and Procurement Guide

When I procure 2-Bromophenylboronic acid, CAS 244205-40-1, I treat it as a functional organic intermediate that requires identity confirmation, specification alignment, and document review before price comparison. The compound is commonly identified as 2-bromobenzeneboronic acid, with the molecular formula C₆H₆BBrO₂ and a reported molecular weight of approximately 200.83 g/mol. I recommend that buyers confirm the CAS number, structure, purity basis, packaging, and available analytical documents with the supplier before placing a purchase order.

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This guide is designed for research organizations, pharmaceutical and agrochemical development teams, custom synthesis companies, distributors, and procurement departments sourcing this material for laboratory or manufacturing use. It does not replace a supplier’s current certificate of analysis, safety data sheet, or regulatory assessment. For a reliable quotation, I provide the intended grade, quantity, delivery destination, required documents, and target delivery window in the first inquiry.

Who This Procurement Guide Is For

I recommend this framework for buyers who need more than a catalog listing or a single spot price. It is especially useful when the material will enter a palladium-catalyzed coupling workflow, process-development study, analytical method, or a controlled inventory system. It can also help distributors compare manufacturers on documentation, batch consistency, packaging, and supply continuity.

Buyers should separate early-stage research needs from regulated or scale-up requirements. A small laboratory purchase may prioritize availability and pack size, while a process-development project may require larger quantities, lot-to-lot consistency, traceability, and a defined change-control process. The appropriate supplier is therefore the one that matches the complete purchasing specification, not necessarily the one offering the lowest nominal price.

Basic Chemical Identity and Function

2-Bromophenylboronic acid contains both an aryl bromide and a boronic acid functionality on a benzene ring. This combination can make the molecule useful as a bifunctional building block in synthetic chemistry, particularly where the boronic acid is selected for a cross-coupling step while the aryl bromide may support further transformation or influence route design. Actual reactivity depends on the reaction system, substrate, catalyst, base, solvent, water content, temperature, and handling conditions.

According to PubChem, the substance identity is associated with CAS 244205-40-1 and the molecular formula C₆H₆BBrO₂; PubChem also reports a molecular weight of about 200.83 g/mol. I use this information as an identity cross-check rather than as a substitute for batch-specific quality testing. Buyers should compare the supplier’s structure, CAS number, formula, molecular weight, and analytical data against the purchasing specification. Source: PubChem, National Center for Biotechnology Information.

Typical Application Contexts

• Medicinal chemistry: use as an aryl building block during analogue preparation and route exploration.
• Process research: evaluate as a defined input for reaction development, impurity studies, and scale-up experiments.
• Custom synthesis: include in multi-step synthesis programs where documented identity and lot traceability are important.
• Academic and industrial research: use in laboratory-scale investigations where the required grade and quantity are clearly defined.

These are application categories rather than guaranteed performance claims. I advise buyers to verify reaction suitability through their own technical evaluation, because boronic acid stability and coupling performance can vary with storage history, impurity profile, and process conditions. A supplier can provide analytical documents and technical discussion, but the end user remains responsible for validating the compound in the intended reaction.

Specification Overview: What Buyers Should Confirm

I begin a specification review with the minimum identity and quality fields shown below. The numerical values for purity, water, residual solvents, and other impurities should be agreed between buyer and supplier rather than assumed from a generic product page. If the material is intended for a regulated or commercial process, the specification should be approved by the buyer’s quality and technical teams before order confirmation.

For procurement purposes, I would not use “high purity” as a sufficient specification because it has no consistent commercial meaning without a test method and acceptance limit. A buyer might request a target such as 98.0% or 99.0% purity, but the correct value depends on the reaction, stage of development, and impurity tolerance. The quotation should state whether the result is a chromatographic area percentage, assay by another method, or a different basis.

Supplier Selection Framework

1. Confirm Identity Before Comparing Price

I first ask the supplier to confirm that the offered product is specifically 2-Bromophenylboronic acid and not 3-bromophenylboronic acid, 4-bromophenylboronic acid, or a protected boronate ester. The CAS number, molecular structure, molecular formula, and molecular weight should be consistent across the quotation, CoA, SDS, label, and shipping documents. This simple document comparison can prevent an expensive mismatch at the receiving or reaction stage.

2. Review the Batch Documentation

I request a representative or current-batch CoA whenever possible, together with an SDS and product specification. The CoA should identify the lot or batch number, test date, test method, result, and release status. For projects requiring stronger traceability, I also ask about manufacturing location, retest or expiry information, change notification, and whether retained samples or additional analytical support are available.

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The Globally Harmonized System provides an internationally recognized framework for hazard communication through labels and safety data sheets, although local implementation differs by jurisdiction. I therefore compare the supplier’s SDS with the destination-country requirements and ask the supplier to confirm the applicable transport and labeling information. Source: United Nations Economic Commission for Europe, GHS Revision 10.

3. Match Grade, Quantity, and Delivery Requirements

Quantity should be stated in a defined unit, such as 10 g, 100 g, 1 kg, or 5 kg, and the buyer should clarify whether the requested amount is a one-time purchase or a recurring forecast. Lead time should be quoted in business days or calendar days and should distinguish in-stock material from made-to-order production. I also ask whether the quoted lead time begins after purchase-order approval, payment, technical confirmation, or another milestone.

MOQ is not a fixed property of the chemical; it is a commercial condition determined by inventory, packaging, production planning, and shipment economics. A supplier may offer a small pack for laboratory evaluation and a different MOQ for kilogram-scale supply. The most useful quotation therefore includes pack size, available quantity, MOQ, lead time, shelf-life or retest information, shipping terms, and validity period.

4. Evaluate the Total Procurement Cost

I compare total landed cost rather than unit price alone. The calculation may include product price, packaging, documentation fees, dangerous-goods handling if applicable, freight, customs, taxes, sampling, and any additional analytical testing. A 10% lower unit price may not be economically attractive if the supplier has a longer lead time, a larger MOQ, or weaker batch documentation.

For recurring demand, I ask suppliers to quote several quantity tiers, such as 100 g, 500 g, 1 kg, and 5 kg, only when those quantities are relevant to the project. I also request confirmation that the same specification can be maintained across different pack sizes. This helps distinguish a genuine scale-up supply option from a one-off laboratory listing.

Common Procurement Mistakes

• Comparing CAS numbers without checking structures: positional isomers may have different reactivity and commercial availability.
• Accepting an unspecified purity claim: ask for the analytical method, result basis, and acceptance limit.
• Ignoring water and storage history: boronic acid materials should be assessed according to the supplier’s handling guidance and the buyer’s process sensitivity.
• Ordering before document approval: obtain the SDS, specification, and CoA requirements before releasing the purchase order.
• Using an unqualified delivery estimate: separate stock availability, production time, dispatch time, and customs time.

I also avoid assuming that a research-grade material is automatically suitable for manufacturing. The required documentation, impurity controls, packaging, and change-notification expectations can be substantially different. If the compound will support a regulated development program, I recommend involving quality assurance, regulatory, and process chemistry stakeholders before supplier approval.

How Maison Chemical Can Support Your Inquiry

At Maison Chemical, I approach 2-Bromophenylboronic acid sourcing as a specification-matching exercise rather than a simple product-price transaction. I can organize an inquiry around CAS 244205-40-1, requested quantity, target purity, packaging, delivery destination, and document requirements. Where a standard catalog specification does not match the project, I recommend discussing the required analytical package before quotation acceptance.

For each inquiry, I encourage buyers to provide the intended use, quantity range, required delivery date, and whether the material is for screening, process development, or routine production. I can then help clarify which information is available for the proposed lot, which tests are standard, and which requirements may need separate confirmation. Any final specification, price, MOQ, and lead time should be confirmed in the formal quotation because they depend on batch availability and destination.

Buyer Checklist Before Placing an Order

1. Confirm the product name, CAS 244205-40-1, structure, formula, and approximate molecular weight of 200.83 g/mol.
2. Define the required purity target and analytical basis, such as HPLC area % or another agreed method.
3. Request a current or representative CoA, SDS, product specification, and available analytical data.
4. Confirm pack size, net quantity, MOQ, batch availability, and lead time in writing.
5. Review packaging, labeling, storage guidance, shipping terms, and destination-country requirements.
6. Agree on acceptance criteria, document approval, deviation handling, and change notification for repeat supply.
7. Compare total landed cost and supply risk instead of comparing unit price alone.

Summary and Next Steps

2-Bromophenylboronic acid CAS 244205-40-1 is a defined aryl boronic acid intermediate with the formula C₆H₆BBrO₂ and an approximate molecular weight of 200.83 g/mol. The best procurement decision depends on verified identity, agreed purity and impurity limits, batch-specific documentation, suitable packaging, and realistic delivery terms. I recommend qualifying the supplier through documents and a clear specification before evaluating the final commercial offer.

To request a quotation from Maison Chemical, send the required quantity, target grade or purity, delivery country, preferred pack size, desired delivery window, and document requirements. I can use those details to prepare a more relevant supply discussion for laboratory evaluation, process development, or recurring B2B procurement. Final product availability, price, MOQ, lead time, and analytical documentation will be confirmed against the proposed batch and order conditions.

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