2-Bromopyridine-5-carbaldehyde, CAS 149806-06-4, is a brominated pyridine aldehyde used primarily as a synthetic building block and pharmaceutical intermediate. Its two reactive features—a bromine substituent and an aldehyde group—allow chemists to plan further coupling, condensation, reduction, oxidation, and heterocyclic synthesis steps. At Maison Chemical, I help buyers evaluate this material by identity, purity requirements, packaging, documentation, and supply conditions rather than by name alone.
The commonly associated molecular formula is C6H4BrNO, with a calculated molecular weight of approximately 186.01 g/mol. Because commercial specifications can differ by grade, intended reaction, and analytical method, I recommend confirming the latest certificate of analysis, appearance, assay, water content, residual solvents, and impurity profile before purchase. This guide explains how to select and source the product for laboratory development, process research, and intermediate manufacturing.
I prepared this guide for procurement specialists, research chemists, process development teams, contract manufacturers, and distributors who need a practical overview of CAS 149806-06-4. It is useful when comparing suppliers, preparing an internal material specification, or moving from milligram-scale screening to larger development quantities. It can also support buyers who need to distinguish a catalog listing from a properly documented commercial supply.
This page is not a substitute for a project-specific risk assessment or a validated analytical method. The appropriate specification depends on the reaction sequence, impurity sensitivity, regulatory expectations, and final application. For that reason, I treat the stated product identity as the starting point and confirm the remaining requirements with the buyer.
2-Bromopyridine-5-carbaldehyde contains a pyridine ring bearing bromine at the 2-position and a carbaldehyde group at the 5-position. The pyridine nitrogen contributes heteroaromatic character, while the aldehyde group can participate in common carbonyl transformations. The aryl bromide can also serve as a functional handle in suitable cross-coupling or substitution strategies, subject to the reaction conditions selected by the chemist.
The combination of these functional groups gives the molecule value as a versatile intermediate, but it also means that buyers should consider chemical stability and handling during storage and use. Aldehydes may require protection from conditions that promote oxidation or unwanted reactions, while heteroaromatic bromides may be sensitive to strongly reactive formulations. I recommend that each laboratory confirm compatibility through its own small-scale evaluation.
| Item | Information | Buyer Check |
|---|---|---|
| Product name | 2-Bromopyridine-5-carbaldehyde | Confirm nomenclature and positional isomer |
| CAS number | 149806-06-4 | Match the purchase order and documentation |
| Molecular formula | C6H4BrNO | Check against the supplier’s current specification |
| Calculated molecular weight | Approximately 186.01 g/mol | Use for stoichiometric planning and analytical review |
A buyer should request a current specification sheet and batch-specific certificate of analysis before approving a supply. The most relevant items normally include visual description, identification, assay or purity, related substances, water content, residual solvents, and any project-specific elemental or inorganic limits. I avoid presenting a single universal purity value because the correct acceptance criterion depends on the intended synthesis and the supplier’s validated analytical method.
Analytical confirmation may include chromatographic testing for assay and related substances, together with spectroscopic or other identity testing. The exact techniques, reporting limits, and acceptance criteria should be stated in the supplier documentation rather than assumed from a product page. If the material will enter a regulated development program, the buyer should also clarify document expectations, change-control communication, and traceability requirements at the quotation stage.
The main application area for 2-Bromopyridine-5-carbaldehyde is synthetic research involving substituted pyridine frameworks. Medicinal chemistry teams may use it to introduce a pyridine-containing fragment into exploratory molecules, while process groups may investigate it as a precursor in a longer route. Its utility is route-dependent, so I recommend evaluating both functional-group compatibility and impurity carryover before selecting a commercial grade.
The aldehyde group can support transformations such as condensation with suitable amines or other nucleophilic partners. The brominated position may provide a separate opportunity for coupling or further substitution, depending on catalyst, base, solvent, and reaction design. These are general synthetic possibilities, not guaranteed outcomes; each reaction must be established and validated by the customer’s technical team.
Other potential users include specialty chemical developers and academic or contract research laboratories working with heteroaromatic intermediates. The material may be suitable for route scouting, analog preparation, and process feasibility work when the required analytical profile is understood. It should not be described as an active pharmaceutical ingredient or as an approved pharmaceutical component unless the buyer has separate regulatory evidence for the final product.
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Start by identifying whether the material is needed for discovery chemistry, process development, analytical reference work, or commercial intermediate production. Discovery projects may prioritize availability and small-pack flexibility, while process development typically requires tighter impurity control and stronger batch-to-batch documentation. Commercial programs should define the specification before requesting scale-up pricing.
Do not select purity only by comparing a single percentage on a quotation. Review the impurity types, because an impurity that appears minor by total assay may still interfere with a sensitive coupling, crystallization, or downstream purification. I can help buyers organize a specification request around the actual route and the impurities most likely to affect performance.
Ask suppliers to quote the quantities that reflect the project stage, such as 1 g for initial screening, 10 g or 100 g for broader laboratory work, and kilogram quantities for process evaluation. These quantities are planning examples, not fixed commercial pack sizes, and availability should be confirmed for each order. Packaging should protect the material from contamination and provide clear lot identification throughout internal handling.
A suitable supplier should be able to explain the available documentation, production or sourcing route, quality-control process, and expected lead time. Buyers should also ask whether repeat batches can be compared using consistent analytical criteria. For projects with a longer development cycle, early discussion of forecast volumes and change notification can reduce avoidable sourcing risk.
The price of CAS 149806-06-4 can vary with purity target, order quantity, packaging, testing requirements, and shipping destination. A small research pack generally has a different cost structure from a development-scale order because testing, handling, and packaging costs are distributed differently. I therefore recommend requesting a tiered quotation rather than relying on one unit price.
Minimum order quantity is not necessarily a chemical property; it is a commercial and operational condition. Maison Chemical can review the requested quantity, intended use, destination, and documentation requirements before confirming an appropriate offer. Lead time should likewise be confirmed against current inventory and production planning, rather than inferred from a generic product listing.
When I compare suppliers, I focus first on whether the company can clearly identify the correct compound and provide traceable batch information. I then review the quality specification, analytical support, packaging, communication speed, and ability to handle repeat requirements. A lower quoted price is not necessarily the best value if the material requires additional qualification or creates uncertainty in a time-sensitive synthesis program.
At Maison Chemical, I support buyers with product identification, specification alignment, quotation preparation, and export coordination for pharmaceutical and specialty chemical intermediates. Our role is to translate a technical request into clear commercial details, including quantity, purity expectations, packaging, documentation, and destination requirements. Where a project has unusual analytical or delivery needs, I recommend discussing them before the purchase order is issued.
We can evaluate inquiries for laboratory quantities, development quantities, and larger supply requirements according to current availability and confirmed production conditions. I do not treat a generic specification as a substitute for project qualification, so the final offer should be based on the buyer’s required grade and documentation package. This approach helps both sides identify potential gaps before shipment.
If you are evaluating 2-Bromopyridine-5-carbaldehyde CAS 149806-06-4, first send the required quantity, target purity or impurity limits, intended application, destination country, and desired delivery schedule. If you already have an internal specification, include it with the inquiry so I can review the request more accurately. For a new route, a sample or small qualification quantity may be a practical first step before moving to larger volume.
Contact Maison Chemical with your technical and commercial requirements for a focused quotation. I can help confirm product identity, available documentation, packaging options, MOQ, and lead-time expectations. The best purchasing decision is the one that matches the material’s documented quality with the chemistry, scale, and compliance needs of your project.
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